POLR2J Antibody, HRP conjugated

Datasheet

Code	CSB-PA347112LB01HU
Size	US$166
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) POLR2J Polyclonal antibody

Uniprot No.

P52435

Target Names

POLR2J

Alternative Names

DNA directed RNA polymerase II subunit RPB11 a antibody; DNA-directed RNA polymerase II 13.3 kDa polypeptide antibody; DNA-directed RNA polymerase II 13.3 kDa polypeptide antibody; DNA-directed RNA polymerase II subunit J 1 antibody; DNA-directed RNA polymerase II subunit J-1 antibody; DNA-directed RNA polymerase II subunit RPB11-a antibody; hRPB 14 antibody; hRPB14 antibody; POLR 2J1 antibody; POLR2J antibody; POLR2J1 antibody; polymerase (RNA) II (DNA directed) polypeptide J 13.3kDa antibody; polymerase (RNA) II (DNA directed) polypeptide J 13.3kDa antibody; RNA polymerase II 13.3 kDa subunit antibody; RNA polymerase II subunit B11 a antibody; RNA polymerase II subunit B11-a antibody; RPB 11 antibody; RPB 11A antibody; RPB 11m antibody; RPB11 antibody; RPB11_HUMAN antibody; RPB11a antibody; RPB11m antibody; Rpo2-4 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human DNA-directed RNA polymerase II subunit RPB11-a protein (1-117AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

HRP

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB11 is part of the core element with the central large cleft.

Gene References into Functions

POLR2J interacts with three different subunits of eIF3, eIF3a, eIF3i, and eIF3m. PMID: 22022972
Four independent genes(POLR2J1, POLR2J2, POLR2J3, POLR2J4) encoding various variants of the hRPB11 subunit of Homo sapiens RNA polymerase II were revealed in human chromosome 7 PMID: 15586814

Subcellular Location

Nucleus.

Protein Families

Archaeal RpoL/eukaryotic RPB11/RPC19 RNA polymerase subunit family

Tissue Specificity

Ubiquitously expressed. High expression was found in heart and skeletal muscle.

Database Links

HGNC: 9197

OMIM: 604150

KEGG: hsa:5439

STRING: 9606.ENSP00000292614

UniGene: Hs.654952

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Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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